Human Nutrition


Mother’s Gift for Health Across Life Stages

Research has shown that 2'-FL supports the development of healthy gut and immune system, protection against allergic diseases and plays a role in the development of normal brain functions and cognition in early life and beyond.

What is 2’FL?  

2'-FL is a component of Human Milk Oligosaccharides (HMO), complex carbohydrates that are naturally present in breast milk. HMOs have been identified as the key differentiating factor between human and bovine milk. For the majority of mothers, 2'-FL is the most abundant HMO in their breast milk.


What makes BASF’s PREBILAC® 2'-FL unique?

Large-scale production and supply reliability for sustainable business development

BASF has successfully mastered the complete in-house development of 2'-FL from strain development to downstream processing using a specifically stable HMO fermentation strain designed for large-scale production.

BASF's in-house expertise in process development ensures reliable production set-up and our upscaling capabilities provide flexibility to consistently meet customer needs.

With BASF's leadership in production technology and operative excellence, you can be assured that we will provide the most reliable and efficient production set-up for 2'-FL.

Commitment to uncompromised safety and quality

Selection of stable fermentation strains enables BASF to have a consistent quality of 2'-FL without the use of antibiotics during production. BASF has long-standing expertise in health ingredients for serving food and supplement markets, including specific regulatory and quality requirements for infant nutrition. We fully focus on safety & quality of our products (Food Safety Certification and cGMP-Food (USA), production under HACCP, compliance with legal requirements on hygienic practice for infant food, Kosher and Halal certification).

Solid scientific foundation for progressive health solutions

Through collaboration with global thought leaders in the field of HMOs, BASF is extending and driving the scientific evidence base for 2'-FL and thus unlocking further benefit areas and opportunities in the market.

Applications of PREBILAC® 2'-FL

BASF’s global network of application laboratories offers first class application services, tailor-made training and technical support for infant nutrition, dietary supplements, as well as functional and medical nutrition. With the launch of PREBILAC® 2'-FL, BASF is able to partner customers to drive further health solutions across all stages of life.


Infant Nutrition

Human milk is the “gold standard” for infant nutrition. Compared with infant formula, breast-feeding leads to favorable results with respect to growth patterns, nutritional status, immune protection and long-term development outcomes. Thus, a lot of efforts are made to narrow the nutritional gap between human milk and infant formula, which are largely based on cow's milk.
The availability of 2'-FL for use in infant formula is an important milestone that narrows the nutritional gap between infant formula and the gold standard for infant nutrition, human milk.
2'-FL is the most thoroughly researched single HMO so far. In addition to observational studies suggesting strong associations between the presence of high levels of 2'-FL and positive health outcomes in infants, benefits have recently been substantiated in clinical and experimental trials.


Digestive Health Across Life Stages

PREBILAC® 2'-FL is a prebiotic based on human breast milk - a mother's gift. PREBILACTM is patent-protected for broad use beyond infant nutrition in dietary supplements, functional nutrition and medical food. Patents covering these uses have been successfully granted in Japan and the United States, while patent applications on these uses have been filed or sought in other markets.

Backed by science, 2'FL has been shown to be vital for digestive health by promoting growth of beneficial bacteria, inhibit adhesion of pathogens, quenching inflammation and normalizing gut movements. These apply to various life stages besides in infants.

The digestive support segment comprises 10% of the global dietary supplement market.

For more information, our team is ready to provide support. Contact us at

Application Areas


Pregnancy & Early Life Health

During the first 1000 days of baby’s life, we deliver the right nutrients for both the healthy development of the child and the wellbeing of the pregnant mother.

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Infant & Maternal Nutrition

Since many years, the global infant nutrition market experiences strong growth and is forecasted to continue doing so.

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